Mathematical Modeling and Validation in Physiology : Applications to the Cardiovascular and Respiratory Systems / edited by Jerry J. Batzel, Mostafa Bachar, Franz Kappel
(Lecture Notes in Mathematics ; 2064)
| データ種別 | 電子ブック |
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| 出版情報 | Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer , 2013 |
| 本文言語 | 英語 |
| 大きさ | XX, 254 p. 83 illus., 34 illus. in color : online resource |
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| 内容注記 | 1 Merging Mathematical and Physiological Knowledge: Dimensions and Challenges 2 Mathematical Modeling of Physiological Systems 3 Parameter Selection Methods in Inverse Problem Formulation 4 Application of the Unscented Kalman Filtering to Parameter Estimation 5 Integrative and Reductionist Approaches to Modeling of Control of Breathing 6 Parameter Identification in a Respiratory Control System Model with Delay 7 Experimental Studies of Respiration and Apnea 8 Model Validation and Control Issues in the Respiratory System 9 Experimental Studies of the Baroreflex 10 Development of Patient Specific Cardiovascular Models Predicting Dynamics in Response to Orthostatic Stress Challenges 11 Parameter Estimation of a Model for Baroreflex Control of Unstressed Volume |
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| 一般注記 | This volume synthesizes theoretical and practical aspects of both the mathematical and life science viewpoints needed for modeling of the cardiovascular-respiratory system specifically and physiological systems generally. Theoretical points include model design, model complexity and validation in the light of available data, as well as control theory approaches to feedback delay and Kalman filter applications to parameter identification. State of the art approaches using parameter sensitivity are discussed for enhancing model identifiability through joint analysis of model structure and data. Practical examples illustrate model development at various levels of complexity based on given physiological information. The sensitivity-based approaches for examining model identifiability are illustrated by means of specific modeling examples. The themes presented address the current problem of patient-specific model adaptation in the clinical setting, where data is typically limited |
| 著者標目 | Batzel, Jerry J. editor Bachar, Mostafa editor Kappel, Franz editor SpringerLink (Online service) |
| 件 名 | LCSH:Mathematics LCSH:Human physiology LCSH:Bioinformatics LCSH:Computational biology LCSH:Biomathematics FREE:Mathematics FREE:Mathematical and Computational Biology FREE:Human Physiology FREE:Computer Appl. in Life Sciences |
| 分 類 | DC23:570.285 |
| 巻冊次 | ISBN:9783642328824 
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| ISBN | 9783642328824 |
| URL | http://dx.doi.org/10.1007/978-3-642-32882-4 |
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